The Great Doxology is an ancient hymn of praise to the Trinity which is chanted or read daily in the Eastern Orthodox and Greek-Catholic Churches.

Glory to God in the highest,
and on earth peace, good will among men.
We praise Thee, we bless Thee,
we worship Thee, we glorify Thee,
we give thanks to Thee for Thy great glory.
O Lord, heavenly King, God the Father Almighty;
O Lord, the Only-Begotten Son, Jesus Christ; and O Holy Spirit.
O Lord God, Lamb of God, Son of the Father,
that takest away the sin of the world, have mercy on us;
Thou that takest away the sins of the world, receive our prayer;
Thou that sittest at the right hand of the Father, have mercy on us.
For Thou only art holy,
Thou only art the Lord, O Jesus Christ, to the glory of God the Father. Amen.
Every day will I bless Thee and I will praise Thy name forever, yea forever and ever.
Vouchsafe, O Lord, to keep us this day without sin.
Blessed art Thou, O Lord, the God of our fathers,
and praised and glorified is Thy name unto the ages. Amen.
Let Thy mercy, O Lord, be upon us according as we have hoped in Thee.
Blessed art Thou, O Lord, teach me Thy statutes.
Blessed art Thou, O Lord, teach me Thy statutes.
Blessed art Thou, O Lord, teach me Thy statutes.
Lord, Thou hast been our refuge in generation and generation.
I said: O Lord, have mercy on me, heal my soul, for I have sinned against Thee.
O Lord, unto Thee have I fled for refuge, teach me to do Thy will, for Thou art my God;
For in Thee is the fountain of life, in Thy light shall we see light.
O continue Thy mercy unto them that know Thee.
Holy God, Holy Mighty, Holy Immortal, have mercy on us.
Holy God, Holy Mighty, Holy Immortal, have mercy on us.
Holy God, Holy Mighty, Holy Immortal, have mercy on us.
Glory to the Father, and to the Son, and to the Holy Spirit, both now and ever, and unto the ages of ages. Amen.
Holy Immortal, have mercy on us.
Holy God, Holy Mighty, Holy Immortal, have mercy on us.
The hymn is based on Luke 2:14 in which the angelic host appears to the shepherds and announces to them the Nativity of Christ. The hymn also incorporates verses from Psalm 145:2 and Psalm 119:12. The hymn is one of the most famous liturgical exclamations of praise (doxology) in the history of the Christian Church.

The Great Doxology comes from an ancient Greek hymn dating from at least the 3rd century, and perhaps even the 1st century. A very similar form is found in the Codex Alexandrinus (5th century) and in Pseudo-Athanasius (sometime prior to the 4th century). The hymn has been extended further than these earlier examples (and what could be interpreted as allusions to subordinationism have been corrected).

The Great Doxology has some similarities to Polycarp's final prayer before his martyrdom, as it is recorded by Eusebius. "I praise Thee for all, I bless Thee, I glorify Thee..." Polycarp is said to have been martyred 156-167 A.D.

As currently used, the hymn is found in several different forms: